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Important Safety Information

If you have a pelvic or genital infection, get infections easily, or have certain cancers, don't use Kyleena. Less than 1% of users get a serious pelvic infection called pelvic inflammatory disease (PID). ... Continue below

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Kyleena IUD Placement

Understanding what happens before, during, and after placement

Once you and your healthcare provider decide that Kyleena® is right for you, they’ll schedule an appointment for it to be placed. Sometimes this can be done during the same office visit. If not, you’ll make another appointment to come back.


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Before having Kyleena placed, tell your healthcare provider about all of your medical conditions including if you:

  • have any of the conditions listed here

  • have had a heart attack

  • have had a stroke

  • were born with heart disease or have problems with your heart valves

  • have problems with blood clotting or take medicine to reduce clotting

  • have high blood pressure

  • recently had a baby or are breastfeeding

  • have severe headaches or migraine headaches

  • have AIDS, HIV, or any other sexually transmitted infection

HCP explaining health needs with patient

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking the mystery out of the placement procedure

Many women have concerns about the placement of Kyleena. Often, learning all you can about what to expect can help:


    Kyleena can be placed during a routine office visit or immediately after giving birth. You may experience pain, bleeding or dizziness during and after placement. If your symptoms do not pass within 30 minutes after placement, Kyleena may not have been placed correctly. Your healthcare provider will examine you to see if Kyleena needs to be removed or replaced.

    Kyleena is placed by your healthcare provider during a routine office visit or immediately after giving birth.

    First, your healthcare provider will examine your pelvis to find the exact position of your uterus. Then they will clean your vagina and cervix with an antiseptic solution. Next, they will slide a slim plastic tube containing Kyleena through the cervix into your uterus, then remove it, leaving Kyleena in place, and cut the threads to the right length.

    If pain is a concern for you, ask your healthcare provider about taking over-the-counter pain medication before the procedure. 

    You should check that Kyleena is in proper position by feeling the removal threads. It is a good habit to do this once a month.


    Your healthcare provider should teach you how to do this. First, wash your hands with soap and water. You can check by reaching up to the top of your vagina with clean fingers to feel the removal threads. Do not pull on the threads. If you feel more than just the threads or if you cannot feel the threads, Kyleena may not be in the right position and may not prevent pregnancy. Avoid intercourse or use non hormonal back-up birth control (such as condoms or spermicide) until you can be seen by your healthcare provider who can confirm if Kyleena is still in place.

    You should return to your healthcare provider for a follow-up visit 4 to 6 weeks after Kyleena is placed to make sure that it is in the right position. Otherwise, call your healthcare provider if you have any questions or concerns, or for any of these reasons.

    If Kyleena is accidentally removed and you had vaginal intercourse within the preceding week, you may be at risk of pregnancy, and you should talk to a healthcare provider.


    Call your healthcare provider if you have any concerns about Kyleena. Be sure to call if you:

    • think you are pregnant
    • have pelvic pain, abdominal pain, or pain during sex
    • have unusual vaginal discharge or genital sores
    • have unexplained fever, flu-like symptoms or chills
    • might be exposed to sexually transmitted infections (STIs)
    • are concerned that Kyleena may have been expelled (came out)
    • cannot feel Kyleena’s threads
    • develop very severe or migraine headaches
    • have yellowing of the skin or whites of the eyes. These may be signs of liver problems
    • have had a stroke or heart attack
    • become HIV positive, or your partner becomes HIV positive
    • have severe vaginal bleeding or bleeding that concerns you

    Kyleena and your period

    3 to 6 months

    Your periods are likely to change while using Kyleena. During the first 3 to 6 months, bleeding and spotting days may increase, and your period may become irregular. Some women have heavy bleeding during this time. You may also have cramping during the first few weeks.

    Downward trending arrow

    Once your body adjusts, monthly bleeding usually decreases. Kyleena contains a small amount of a hormone that may reduce the monthly thickening of your uterine lining. This thinning of the uterine lining can reduce monthly bleeding.

    Changes with duration in time

    Over time, your periods are likely to become shorter and lighter, or they may stop entirely. When Kyleena is removed, your periods should return.


    About 12 out of 100 women stop having periods after 1 year of Kyleena use. If you do not have a period for 6 weeks during Kyleena use, call your healthcare provider.


    Because Kyleena is placed in the uterus, not in the vagina, you can still use tampons while using Kyleena. 

    Kyleena and sex

    Because Kyleena sits in your uterus and not your vagina, you should not be able to feel it after it has been placed. You and your partner should not be able to feel Kyleena during sex. Sometimes, your partner may be able to feel the threads. If this happens, or if you or your partner experience pain during sex, talk with your healthcare provider.

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    Facts about IUDs

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    Kyleena® (levonorgestrel-releasing intrauterine system) is a hormone-releasing IUD that prevents pregnancy for up to 5 years.



    • If you have a pelvic or genital infection, get infections easily, or have certain cancers, don't use Kyleena. Less than 1% of users get a serious pelvic infection called pelvic inflammatory disease (PID).
    • If you have persistent pelvic or stomach pain, or excessive bleeding after placement tell your healthcare provider (HCP). If Kyleena comes out, call your HCP and avoid intercourse or use non-hormonal back-up birth control (such as condoms or spermicide). Kyleena may go into or through the wall of the uterus and cause other problems.
    • Pregnancy while using Kyleena is uncommon but can be life threatening and may result in loss of pregnancy or fertility.
    • Ovarian cysts may occur but usually disappear.
    • Bleeding and spotting may increase in the first 3 to 6 months and remain irregular. Periods over time usually become shorter, lighter, or may stop.


    Kyleena does not protect against HIV or STIs.


    Only you and your HCP can decide if Kyleena is right for you. Kyleena is available by prescription only.


    For important risk and use information about Kyleena, please see Full Prescribing Information.